This pork tenderloin sandwich is a delightful combination of juicy, seasoned pork, fresh vegetables, and creamy mayonnaise, all nestled in a perfectly toasted bun. It's a simple yet satisfying meal that can be prepared quickly, making it perfect for a weeknight dinner or a casual weekend lunch.
Pork tenderloin is the star of this recipe, and while it may not be a staple in every household, it's readily available at most supermarkets. Make sure to pick a tenderloin that is fresh and has a good color. The other ingredients like sandwich buns, shredded lettuce, sliced tomato, and mayonnaise are common and should be easy to find.

Ingredients For Pork Tenderloin Sandwich Recipe
Pork tenderloin: The main protein of the dish, known for its tenderness and mild flavor.
Sandwich buns: These will hold all the delicious components of the sandwich together.
Shredded lettuce: Adds a fresh, crisp texture to the sandwich.
Sliced tomato: Provides juiciness and a slight tang to balance the flavors.
Mayonnaise: Adds creaminess and a bit of richness to the sandwich.
Salt: Enhances the natural flavors of the pork.
Black pepper: Adds a hint of spice and depth to the seasoning.
Technique Tip for This Recipe
When preparing the pork tenderloin, ensure it is evenly seasoned with salt and black pepper for a balanced flavor. To achieve a perfectly cooked tenderloin, use a meat thermometer to check that the internal temperature reaches 145°F (63°C). This ensures the meat is juicy and tender. Additionally, let the pork rest for a few minutes after cooking to allow the juices to redistribute, resulting in a more flavorful and moist sandwich.
Suggested Side Dishes
Alternative Ingredients
pork tenderloin - Substitute with chicken breast: Chicken breast is a lean protein that can be similarly tender and juicy when cooked properly.
pork tenderloin - Substitute with turkey tenderloin: Turkey tenderloin offers a similar texture and mild flavor, making it a good alternative.
sandwich buns - Substitute with whole wheat buns: Whole wheat buns provide more fiber and nutrients while maintaining the structure needed for a sandwich.
sandwich buns - Substitute with lettuce wraps: For a low-carb option, lettuce wraps can replace buns while adding a fresh crunch.
shredded lettuce - Substitute with baby spinach: Baby spinach adds a slightly different flavor and more nutrients like iron and vitamins.
shredded lettuce - Substitute with arugula: Arugula offers a peppery taste that can add a unique flavor profile to the sandwich.
sliced tomato - Substitute with roasted red peppers: Roasted red peppers provide a sweet and smoky flavor that complements the other ingredients.
sliced tomato - Substitute with cucumber slices: Cucumber slices add a refreshing crunch and mild flavor.
mayonnaise - Substitute with Greek yogurt: Greek yogurt is a healthier alternative, offering a creamy texture with added protein.
mayonnaise - Substitute with avocado spread: Avocado spread provides healthy fats and a creamy texture similar to mayonnaise.
salt - Substitute with soy sauce: Soy sauce adds a savory umami flavor and can reduce the need for additional salt.
salt - Substitute with sea salt: Sea salt can offer a different mineral content and a slightly different flavor profile.
black pepper - Substitute with white pepper: White pepper provides a similar heat but with a slightly different flavor, often described as more earthy.
black pepper - Substitute with cayenne pepper: Cayenne pepper adds a spicier kick, perfect for those who enjoy a bit more heat.
Alternative Recipes Similar to This Sandwich
How to Store or Freeze This Sandwich
- Allow the pork tenderloin to cool completely before storing. This helps prevent condensation, which can make the meat soggy.
- Slice the pork tenderloin thinly and place it in an airtight container. If you have multiple layers, separate them with parchment paper to avoid sticking.
- Store the pork tenderloin in the refrigerator for up to 3-4 days. For longer storage, freezing is recommended.
- To freeze, wrap individual portions of the sliced pork tenderloin tightly in plastic wrap or aluminum foil. Place the wrapped portions in a freezer-safe bag or container, removing as much air as possible to prevent freezer burn.
- Label the container with the date to keep track of freshness. The pork tenderloin can be frozen for up to 2-3 months.
- When ready to use, thaw the pork tenderloin in the refrigerator overnight. Reheat gently in a skillet over medium heat or in the microwave until warmed through.
- For the sandwich buns, store them in a bread box or a resealable plastic bag at room temperature for up to 2 days. To extend their shelf life, freeze the buns in a freezer-safe bag for up to 1 month.
- To reheat frozen sandwich buns, let them thaw at room temperature or warm them in the oven at 350°F (175°C) for about 5-7 minutes until they are soft and warm.
- Keep the shredded lettuce and sliced tomato fresh by storing them in separate airtight containers in the refrigerator. Use within 2-3 days for the best quality.
- Store the mayonnaise in its original container in the refrigerator. Ensure the lid is tightly sealed to maintain freshness.
How to Reheat Leftovers
Oven Method: Preheat your oven to 350°F (175°C). Wrap the pork tenderloin slices in aluminum foil to keep them moist. Place the wrapped pork on a baking sheet and heat for about 10-15 minutes, or until warmed through. Toast the sandwich buns separately in the oven for the last 5 minutes.
Skillet Method: Heat a non-stick skillet over medium heat. Add a small amount of olive oil or butter to the skillet. Place the pork tenderloin slices in the skillet and heat for 2-3 minutes on each side until warmed through. Toast the sandwich buns in the same skillet until golden brown.
Microwave Method: Place the pork tenderloin slices on a microwave-safe plate and cover with a damp paper towel to prevent drying out. Microwave on medium power for 1-2 minutes, checking halfway through to ensure even heating. Toast the sandwich buns separately in a toaster or toaster oven.
Steam Method: Use a steamer basket over a pot of simmering water. Place the pork tenderloin slices in the basket, cover, and steam for about 5 minutes or until heated through. This method helps retain moisture. Toast the sandwich buns separately.
Air Fryer Method: Preheat your air fryer to 350°F (175°C). Place the pork tenderloin slices in the air fryer basket and heat for 3-5 minutes, shaking the basket halfway through. Toast the sandwich buns in the air fryer for the last 2 minutes.
Essential Tools for This Recipe
Skillet: A flat-bottomed pan used for cooking the pork tenderloin over medium-high heat.
Tongs: Useful for flipping the pork tenderloin in the skillet to ensure even cooking on both sides.
Cutting board: A surface for slicing the cooked pork tenderloin thinly after it has rested.
Knife: Essential for slicing the pork tenderloin and the tomato.
Meat thermometer: Optional, but helpful for checking if the pork tenderloin has reached a safe internal temperature.
Spatula: Handy for toasting the sandwich buns in the skillet until golden brown.
Measuring spoons: Used for measuring the salt and black pepper to season the pork tenderloin.
Mixing bowl: Useful for holding the shredded lettuce and sliced tomato before assembling the sandwich.
Spoon: For spreading mayonnaise on each sandwich bun.
How to Save Time on This Recipe
Pre-slice the pork: Slice the pork tenderloin before cooking to reduce cooking time and ensure even cooking.
Use pre-shredded lettuce: Buy pre-shredded lettuce to save time on preparation.
Pre-toast the buns: Toast the sandwich buns in advance and keep them warm in the oven.
Prepare condiments ahead: Mix the mayonnaise with any desired seasonings ahead of time.
Batch cook: Cook multiple pork tenderloins at once and store leftovers for quick assembly later.

Pork Tenderloin Sandwich Recipe
Ingredients
Main Ingredients
- 1 lb Pork tenderloin
- 4 Sandwich buns
- 1 cup Lettuce shredded
- 1 Tomato sliced
- ½ cup Mayonnaise
- 1 teaspoon Salt
- ½ teaspoon Black pepper
Instructions
- 1. Preheat your skillet over medium-high heat.
- 2. Season the pork tenderloin with salt and black pepper.
- 3. Cook the pork tenderloin in the skillet for about 8-10 minutes on each side, or until fully cooked.
- 4. Let the pork rest for a few minutes, then slice it thinly.
- 5. Toast the sandwich buns in the skillet until golden brown.
- 6. Spread mayonnaise on each bun, then layer with lettuce, tomato, and sliced pork.
- 7. Serve immediately and enjoy!
Nutritional Value
Keywords
Suggested Appetizers and Desserts
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