This delicious pepperoni bread is a perfect appetizer or snack for any occasion. With its gooey mozzarella cheese and savory pepperoni, it's sure to be a hit with everyone. The golden-brown crust brushed with garlic powder and melted butter adds an extra layer of flavor that makes it irresistible.
If you don't usually keep frozen bread dough at home, you might need to pick some up from the supermarket. It's typically found in the frozen foods section. Make sure to thaw it properly before use. Pepperoni and mozzarella cheese are common ingredients, but if you don't have them, they can be easily found in the deli or cheese section.

Ingredients For Pepperoni Bread Recipe
Frozen bread dough: This is the base of the bread and needs to be thawed before use.
Pepperoni: Sliced and used as a filling for the bread, providing a savory and slightly spicy flavor.
Mozzarella cheese: Shredded and used as a filling, it melts beautifully to create a gooey texture.
Melted butter: Brushed on top of the bread to give it a golden-brown crust.
Garlic powder: Sprinkled on top to add a subtle garlic flavor.
Technique Tip for This Recipe
When rolling out the bread dough, ensure it is evenly stretched to avoid thin spots that might tear during baking. Use a light dusting of flour on your surface and rolling pin to prevent sticking. For a more flavorful twist, consider adding a sprinkle of Italian seasoning or Parmesan cheese inside the roll before baking.
Suggested Side Dishes
Alternative Ingredients
thawed frozen bread dough - Substitute with pizza dough: Pizza dough offers a similar texture and can be easily found in most grocery stores.
sliced pepperoni - Substitute with turkey pepperoni: Turkey pepperoni is a leaner option with less fat and calories.
sliced pepperoni - Substitute with salami: Salami provides a similar spicy and savory flavor profile.
shredded mozzarella cheese - Substitute with shredded provolone cheese: Provolone melts well and has a mild flavor that complements the other ingredients.
shredded mozzarella cheese - Substitute with shredded cheddar cheese: Cheddar adds a slightly sharper taste and melts nicely.
melted butter - Substitute with olive oil: Olive oil provides a healthier fat option and adds a subtle flavor.
garlic powder - Substitute with minced garlic: Minced garlic offers a fresher and more robust garlic flavor.
Alternative Recipes Similar to This Dish
How to Store or Freeze This Recipe
- Allow the pepperoni bread to cool completely before storing. This helps prevent condensation, which can make the bread soggy.
- Wrap the pepperoni bread tightly in plastic wrap or aluminum foil to keep it fresh. Alternatively, you can place it in an airtight container.
- Store the wrapped or containerized pepperoni bread at room temperature if you plan to consume it within 2 days. For longer storage, refrigerate it to extend its shelf life up to a week.
- To freeze, wrap the cooled pepperoni bread in plastic wrap, then in aluminum foil to prevent freezer burn. You can also use a freezer-safe ziplock bag.
- Label the wrapped pepperoni bread with the date to keep track of its freshness.
- When ready to enjoy, thaw the pepperoni bread in the refrigerator overnight if frozen.
- For a warm, fresh-out-of-the-oven taste, reheat the pepperoni bread in a preheated oven at 350°F (175°C) for about 10-15 minutes, or until heated through.
- If you're in a hurry, you can also microwave individual slices of pepperoni bread for about 20-30 seconds, though this may result in a softer crust.
How to Reheat Leftovers
Oven Method:
- Preheat your oven to 350°F (175°C).
- Wrap the pepperoni bread in aluminum foil to prevent it from drying out.
- Place the wrapped bread on a baking sheet and heat for about 10-15 minutes, or until warmed through.
- For a crispier crust, unwrap the foil for the last 5 minutes of reheating.
Microwave Method:
- Place a slice of pepperoni bread on a microwave-safe plate.
- Cover it with a damp paper towel to retain moisture.
- Microwave on medium power for 30-45 seconds, checking to ensure it’s heated through.
- Be cautious not to overheat, as the bread can become chewy.
Toaster Oven Method:
- Preheat your toaster oven to 350°F (175°C).
- Place the pepperoni bread directly on the toaster oven rack or on a small baking sheet.
- Heat for about 10 minutes, or until the bread is warmed through and the cheese is melty.
- For an extra crispy crust, you can broil for the last 1-2 minutes, keeping a close eye to avoid burning.
Stovetop Skillet Method:
- Heat a non-stick skillet over medium heat.
- Place slices of pepperoni bread in the skillet.
- Cover the skillet with a lid to help the bread heat evenly.
- Heat for about 2-3 minutes on each side, or until the bread is warmed through and the cheese is melted.
Air Fryer Method:
- Preheat your air fryer to 350°F (175°C).
- Place slices of pepperoni bread in the air fryer basket in a single layer.
- Heat for 3-5 minutes, checking halfway through to ensure even heating.
- This method will give you a nice crispy crust while keeping the inside warm and gooey.
Best Tools for This Recipe
Oven: Used to bake the pepperoni bread at the specified temperature.
Rolling pin: Helps in rolling out the thawed bread dough into a rectangle.
Lightly floured surface: Prevents the dough from sticking while rolling it out.
Baking sheet: Holds the rolled dough while it bakes in the oven.
Pastry brush: Used to brush melted butter on top of the rolled dough.
Knife: Useful for slicing the pepperoni bread after it has cooled.
Measuring cup: Ensures accurate measurement of the pepperoni and mozzarella cheese.
Mixing bowl: Can be used to mix the garlic powder with the melted butter before brushing.
Towel or plastic wrap: Covers the dough while it thaws to prevent it from drying out.
Cooling rack: Allows the bread to cool evenly after baking.
How to Save Time on Making This Recipe
Use pre-sliced pepperoni: Save time by using pre-sliced pepperoni instead of slicing it yourself.
Pre-shredded cheese: Opt for pre-shredded mozzarella cheese to cut down on prep time.
Thaw dough overnight: Thaw the frozen bread dough in the refrigerator overnight to ensure it's ready to use.
Line baking sheet: Use parchment paper to line your baking sheet for easy cleanup.
Quick roll technique: Roll the dough with a rolling pin to achieve an even rectangle faster.

Pepperoni Bread Recipe
Ingredients
Main Ingredients
- 1 loaf Frozen bread dough thawed
- 1 cup Pepperoni sliced
- 1 cup Mozzarella cheese shredded
- 1 tablespoon Butter melted
- 1 teaspoon Garlic powder
Instructions
- Preheat your oven to 375°F (190°C).
- Roll out the thawed bread dough into a rectangle on a lightly floured surface.
- Layer the pepperoni and mozzarella cheese evenly over the dough.
- Roll up the dough tightly, starting from one of the long edges, and pinch the seam to seal.
- Place the rolled dough seam-side down on a greased baking sheet.
- Brush the top with melted butter and sprinkle with garlic powder.
- Bake in the preheated oven for 25 minutes or until golden brown.
- Let cool for a few minutes before slicing and serving.
Nutritional Value
Keywords
Suggested Main Courses and Desserts for This Recipe
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