Grilled Cheese de Mayo is a delightful twist on the classic grilled cheese sandwich. By using mayonnaise instead of butter, you get a perfectly crispy and golden exterior with a rich, creamy flavor. This simple yet delicious recipe is perfect for a quick lunch or a comforting snack.
The ingredients for this recipe are quite common and should be easily found in most households. However, if you don't have mayonnaise on hand, you will need to pick some up at the supermarket. Additionally, make sure you have cheddar or American cheese slices, as these are essential for the gooey, melted center.

Ingredients For Grilled Cheese De Mayo
Bread: The base of the sandwich, providing structure and a canvas for the other ingredients.
Mayonnaise: Used instead of butter to create a crispy, golden exterior with a creamy flavor.
Cheddar: A sharp, flavorful cheese that melts beautifully.
American cheese: A classic choice for grilled cheese, known for its smooth, melty texture.
Technique Tip for This Recipe
To achieve an extra crispy texture, try using a cast iron skillet for even heat distribution. Additionally, spreading a thin layer of butter on the bread before adding the mayonnaise can enhance the flavor and create a beautifully golden crust.
Suggested Side Dishes
Alternative Ingredients
bread - Substitute with sourdough: Sourdough adds a tangy flavor and a chewy texture that complements the cheese.
bread - Substitute with whole wheat bread: Whole wheat bread offers a nuttier flavor and more fiber, making it a healthier option.
mayonnaise - Substitute with butter: Butter provides a rich, creamy texture and a slightly salty taste that enhances the grilled cheese.
mayonnaise - Substitute with Greek yogurt: Greek yogurt adds a tangy flavor and a creamy texture while being lower in fat.
cheddar cheese - Substitute with mozzarella cheese: Mozzarella melts well and has a mild flavor that pairs nicely with various breads.
cheddar cheese - Substitute with Swiss cheese: Swiss cheese offers a nutty and slightly sweet flavor that adds depth to the sandwich.
american cheese - Substitute with provolone cheese: Provolone melts smoothly and has a mild, slightly smoky flavor.
american cheese - Substitute with havarti cheese: Havarti is creamy and buttery, making it an excellent melting cheese for grilled sandwiches.
Other Alternative Recipes Similar to This Dish
How to Store or Freeze This Recipe
- Allow the grilled cheese to cool completely before storing. This prevents condensation, which can make the bread soggy.
- Wrap each sandwich individually in aluminum foil or parchment paper. This helps maintain the crispiness of the bread.
- Place the wrapped sandwiches in an airtight container or zip-top bag. This will keep them fresh and prevent any unwanted odors from seeping in.
- Store the container in the refrigerator if you plan to eat the sandwiches within 2-3 days. For longer storage, place the container in the freezer.
- When ready to reheat, preheat your oven to 350°F (175°C). If frozen, allow the sandwiches to thaw in the refrigerator overnight.
- Place the sandwiches on a baking sheet and heat in the oven for about 10-15 minutes, or until the bread is crispy and the cheese is melted.
- For a quicker option, reheat the sandwiches in a skillet over medium heat. Cook for 3-5 minutes on each side, pressing down gently with a spatula to ensure even heating.
- Avoid using the microwave to reheat, as it can make the bread rubbery and the cheese unevenly melted.
- Enjoy your reheated grilled cheese de mayo with a side of tomato soup or a fresh salad for a delightful meal.
How to Reheat Leftovers
Preheat your oven to 350°F (175°C). Place the grilled cheese on a baking sheet and cover it loosely with aluminum foil to prevent it from drying out. Bake for about 10 minutes, or until the cheese is melted and the bread is crispy.
Use a skillet over medium heat. Place the grilled cheese in the skillet and cover it with a lid. Heat for about 2-3 minutes on each side, or until the cheese is melted and the bread is crispy.
If you're in a hurry, use a microwave. Place the grilled cheese on a microwave-safe plate and cover it with a damp paper towel to keep it from drying out. Microwave on medium power for about 30-45 seconds, or until the cheese is melted. Note: This method may not keep the bread as crispy.
For a quick and efficient method, use a toaster oven. Set the toaster oven to 350°F (175°C) and place the grilled cheese directly on the rack. Heat for about 5-7 minutes, or until the cheese is melted and the bread is crispy.
If you have an air fryer, preheat it to 350°F (175°C). Place the grilled cheese in the air fryer basket and cook for about 3-4 minutes, or until the cheese is melted and the bread is crispy.
Best Tools for This Recipe
Skillet: A flat-bottomed pan used for cooking the grilled cheese on the stovetop.
Spatula: A tool used to flip the sandwiches to ensure even cooking on both sides.
Butter knife: Used to spread the mayonnaise evenly on the bread slices.
Cutting board: A surface to place the bread while spreading the mayonnaise.
Plate: For serving the grilled cheese sandwiches once they are cooked.
Measuring spoons: To measure the exact amount of mayonnaise needed for the recipe.
How to Save Time on Making This Recipe
Preheat the skillet: Preheat your skillet while you prepare the ingredients to save time.
Use pre-sliced cheese: Opt for pre-sliced cheese to avoid the hassle of slicing it yourself.
Assemble in advance: Assemble the sandwiches ahead of time and store them in the fridge until ready to cook.
Cook multiple sandwiches: Use a large skillet or griddle to cook multiple sandwiches at once.
Use a lid: Cover the skillet with a lid to help the cheese melt faster.

Grilled Cheese de Mayo Recipe
Ingredients
Main Ingredients
- 4 slices Bread
- 2 tablespoon Mayonnaise
- 4 slices Cheese Cheddar or American
Instructions
- 1. Spread mayonnaise on one side of each slice of bread.
- 2. Place two slices of bread, mayo side down, on a skillet over medium heat.
- 3. Add cheese slices on top of the bread in the skillet.
- 4. Top with the remaining slices of bread, mayo side up.
- 5. Cook until golden brown, then flip and cook the other side until golden and cheese is melted.
Nutritional Value
Keywords
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